ABSTRACT
With the gradual promotion of the health care reform,improving the management level of public hospitals has become a key breakthrough.Hospital management should not only pay attention to the differences in the property,scale and region,but also pay attention to the differences among different groups within the hospital.Research shows that there are obvious differences between physicians and registered nurses management system,such as staffing,performance management,target management and talent management.The difference has a series of negative influence on relationship between physicians and nurses,so as to impede the efficient clinical work and harm hospital development.It can be changed by increasing the number of medical staff,establishing a scientific evaluation system and communication mechanism.
ABSTRACT
<p><b>OBJECTIVE</b>To examine serum levels of interleukin-13 (IL-13) and tumor necrosis factor alpha (TNF-alpha) in children with Mycoplasma pneumoniae (MP) pneumonia.</p><p><b>METHODS</b>Eighty children with MP pneumonia complicated by wheezing or without (n=40 each), 40 children with pneumonia from non-MP infection and 40 healthy children were enrolled. Serum levels of IL-13 and TNF-alpha were measured using ELISA.</p><p><b>RESULTS</b>The serum levels of IL-13 and TNF-alpha in the MP pneumonia group were significantly higher than those in non-MP pneumonia group and the healthy control group (P<0.01). The children with MP pneumonia complicated by wheezing had increased serum levels of IL-13 (214.6 + or - 67.2 ng/L vs 189.6 + or - 52.1 ng/L; P<0.01) and TNF-alpha(0.55 + or - 0.13 ng/mL vs 0.42 + or - 0.16 ng/mL; P<0.01)compared with those without wheezing.</p><p><b>CONCLUSIONS</b>The increase in serum levels of IL-13 and TNF-alpha may play important roles in the pathogenesis of MP pneumonia and wheezing attack in children.</p>